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The Synthesis of 2-Spiroindolin-3-one-(thio)barbiturates from 2,1-Benzisoxazoles. A Rearrangement Promoted by Thermal Conditions

Authors: P.F. Soeiro; J.L Serrano; J.A. Paixão; R.E.F. Boto; S. Silvestre; P. Almeida

Ref.: Synthesis 52(14), 2065-2072 (2020)

Abstract: This work is supported by funds from the Health Sciences Research Center (CICS-UBI) (UID/Multi/00709/2019) and from CFisUC, Department of Physics (UID/FIS/4564/2019) through National Funds by Fundação para a Ciência e Tecnologia (FCT). This work is also supported by FEDER funds through the POCI–COMPETE 2020–Operational Programme Competitiveness and Internationalization in Axis I–Strengthening research, technological development and innovation [Programa Operacional Competitividade e Internacionalização (COMPETE 2020), project No. 007491)]. J. L. Serrano acknowledges a doctoral fellowship grant from the FCT (SFRH/BD/148028/2019) and a fellowship from Santander-Totta/UBI (BID/ICI-UID FC/Santander Universidades-UBI/2017).

DOI: 10.1055/s-0039-1690865